Acetaminophen Use During Pregnancy & Childhood Behavioral Problem

New research links use of acetaminophen during pregnancy to higher risk for multiple behavioral problems in children. The study, conducted by Evie Stergiakouli, Ph.D., of the University of Bristol, United Kingdom, and colleagues, examined the associations between offspring behavioral problems and maternal prenatal acetaminophen use, maternal postnatal acetaminophen use, and her partner’s acetaminophen use. Conclusions and Relevance: Children exposed to acetaminophen prenatally are at increased risk of multiple behavioral difficulties, and the associations do not appear to be explained by unmeasured behavioral or social factors linked to acetaminophen use insofar as they are not observed for postnatal or partner’s acetaminophen use. Although these results could have implications for public health advice, further studies are required to replicate the findings and to understand mechanisms.