Opioid vs. Non-opioids for Osteoarthritis Pain-Related Function

A recent 12-month study compared the use opioid medication and non-opioid medication for the treatment of 240 Veterans Affairs primary care clinic patients with moderate to severe chronic back pain or hip or knee osteoarthritis pain despite analgesic use.  Findings: The two groups did not differ significantly on pain-related function -the primary outcome. Pain intensity was significantly better in the non-opioid group.  Additionally, adverse medication-related symptoms were more common in the opioid group. Researchers’ Conclusion: "Treatment with opioids was not superior to treatment with non-opioid medications for improving pain-related function over 12 months. Results do not support initiation of opioid therapy for moderate to severe chronic back pain or hip or knee osteoarthritis pain."

https://jamanetwork.com/journals/jama/article-abstract/2673971?redirect=true