Research: Addressing Potentially Inappropriate Prescribing in Older Patients in Primary

Potentially inappropriate prescribing (PIP) is common in older people and can result in increased morbidity, adverse drug events, and hospitalizations. The OPTI-SCRIPT study (Optimizing Prescribing for Older People in Primary Care, a cluster-randomized controlled trial) tested the effectiveness of a multifaceted intervention for reducing PIP in primary care. Participants received an intervention incorporating academic detailing; review of medicines with web- based pharmaceutical treatment algorithms that provide recommended alternative-treatment options; and tailored patient information leaflets. At intervention completion, patients in the intervention group had significantly lower odds of having PIP than patients in the control group.